Bioaccumulation of Environmental Contaminants in Women: Systemic Risks, Reproductive Vulnerability, and Public Health Surveillance Implications
https://doi.org/10.5281/zenodo.15807165
Keywords:
bioacumulação, toxicologia ambiental, saúde da mulher, disruptores endócrinosAbstract
Bioaccumulation of environmental contaminants in women is an emerging threat to public health, affecting reproductive, endocrine, and neurological systems. This integrative review analyzed systematic reviews focused on persistent toxic compounds—such as pesticides, heavy metals, and endocrine disruptors—highlighting their gender-specific effects in human females. The findings indicate distinct mechanisms of accumulation and toxicity influenced by female physiology, including higher adipose tissue, hormonal fluctuations, and critical vulnerability windows (pregnancy and lactation). Documented risks include infertility, cancer, hormonal imbalances, and transgenerational effects. The lack of gender-sensitive public policies and specific surveillance models for women limits institutional responses. This study recommends implementing biomonitoring strategies, territorialized regulatory policies, and the incorporation of gender-sensitive approaches in toxicological and public health assessments.
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